WELCOME TO THE SELFHACKED VIP AREA

Blog

Dashboard

PAST WEBINARS

    VIP #41                                                                                         Nov 4, 2020

Want to Follow Along?

Click here to see questions answered in webinar

Ask Joe

Have a question that hasn’t been answered in this webinar? Ask Joe yourself and have it answered in an upcoming webinar

ASK JOE

Question
Hi Joe, I'm trying to diagnose several changes in my brain and body which began stepping up after the pandemic. The most surprising one happened last night: I woke up and discovered I'd wet my bed, and that I still had plenty of pee in my bladder. When I did pee last night after wetting the bed, the "stream" was "easy" and strong. So I don't think my prostate was enlarged more than usual. FYI I am 66, so its the first time I've wet my bed since I was a child 60 years ago! Prior to this episode, I was trying to find a fix for my insomnia and weight gain and depression during the pandemic. For years, I'd already been taking Clonazepam, and OTC drugs like Melatonin and benadryl at bedtime. I was also on Lyrica for nerve pain which started 13 years ago after I had been diagnosed with Chronic Fatigue, the worst symptoms disappearing after years of no help from doctors, and a risky but effective treatment I developed on my own, with scorpion venom! The venom turned out to be very effective. Within weeks of taking it, my daily chills and feeling of flu diminished significantly. However, one of the symptoms was that I would be awakened at night with pain throughout my body.. so the Dr. prescribed Lyrica which is 90% effective. (And on CFS, even after I recovered significantly, I still need about 10 hours of sleep to feel refreshed the next day. If I don't get solid sleep, I'm worthless, can't focus, have to take naps, and can hardly get anything done during the day. So when the insomnia got really bad a few months ago, I tried CBD which was mildly effective in the beginning. But over the course of a few months, my insomnia got worse. I tried upping the CBD and the benadryl, to no effect. I changed my BP med to clonidine, which had a tremendous effect on making me feel "soothed" and relaxed, stop my racing thoughts, and fall asleep earlier. But then I'd wake after 2 to 4 hours after falling asleep. So I increased my CBD. That (I think) caused me to have nasal congestion during the night, so that just meant further difficulties falling alseep) Then... I asked my Dr if he would change my antidepressant from Zoloft to Prosac. This change was super effective in lifting my mood and my ability to focus. (but I've also noticed a severe drop in short term memory The only other changes I've made in my daily regimen is to take Apple Cider Vinegar by mixing into whatever I'm drinking. Last night I consumed a bit more than normal. I also added MCT 8 to my diet in hopes of burning calories. I wonder if this is causing the insomnia and the other symptoms. I think the only other major change in my health over the last month is that my left leg feels more difficult to control. Between that, and my difficulty balancing myself now, there are times when I walk around as if I were drunk! I know there are so many variables in this equation that it would take forever to find the culprit by eliminating meds and food. But I'm hoping something in my history here raises a red flag for you. Let me know what you think. I hope you're safe and well.
hey joe, I've had inflammation for a while now gut/brain. I am doing carnivore currently to get a good baseline before I try to reintroduce other foods. my question is when you were fixing your problems how did your inflam go down? did you have relief from inflam in a week or so or did it take longer? my inflam has gone down considrebly but i still have some inflam and wanted to know if there would be anything that would help.
hi joe, male/22/ 145lbs/ 6'2"/ I've been suffering from brain fog/ depression/ anxiety from 10. I think a lot of it was childhood trauma and then food sensitivities. I have also had 2 injuries to the head as a kid, I have always noticed being slow = brain fog. around 17 I had a concussion and a bad one my head slammed on concrete I passed out for 3-4 hours and pucked and was foaming after I didn't go to the doctor just power through the headaches and didn't do anything about it, but that's when my problems started to get worse and I started to get severe inflammation after but I didn't think anything of it and over time it got worse and worse. my depression, anxiety, and brain fog skyrocketed and my cognition went to shit. I went on for 2 years eating junk food and rice lentils and sweets. In the past year I have "started eating healthy" = vegetables fruits and chicken. but my condition got better slightly, July 24 I went carnivore cut out everything because I was addicted to carbs and sweets. I would eat but still won't feel full it was a mess. I would eat 30 cookies and still want more. after going carnivore the transition was bad, I was getting fatigued and still had the inflamed, but after supplementing with hi maize and butyrate I felt better. I think it was cause carbs in hi maize that I felt better do you agree? I am now supplementing with curcumin and fish oil, electrolytes, and also take my MTHFR mutation regimen. I am going to start taking lithium and 5-htp soon. now I have been 2 months on carnivore high-fat good amount of protein and some carbs and my inflammation has been down, but I still have like a little bit of it left like its 30% left and it's not going away I don't have anxiety any more depression very rare and my mood is not bad but it's bland like no emotions and brain fog I have low-grade chronic inflammation it feels like I'm almost healthy or "normal" but the last bit of chronic inflammation is stopping me. my question is what do you think I need to get rid of that last bit of inflammation? ices/LLT? anything you would suggest would be helpful. maybe mitochondria supplements anything I am willing to do. also, i want to start adding foods in but once the inflammation is gone then i can tell what i am reacting to. also, my sleep is good I wear blue-blocking glasses 3 hours ahead of bed and sleep just fine 6-8 hours. I am getting a sleep study soon. I also go to the sun 45 mins. I know my problems started young but they weren't severe, but after the concussion, they got really bad. thank you for reading.
joe i have had lots of concussion in the past and have problems from it, I have chronic inflam from it still going on I am going to try some anti-inflammatories. like curucbrain and fish oil. but i also wanted to use ices and came across their study for TBI. please take a look at this study.https://downloads.corticalmetrics.com/pub/corticalmetrics_magazine_issue_1.pdf
hey, joe, 1.thoughts on chicken bought from a store like a rotisserie. do you get inflamed from eating grain-fed chicken? does it generally matter if they are grain-fed or grass-fed if you are getting good quality meat? 2. I have noticed that I get inflamed from working out that makes me sleepy, I also have heard you say you get inflammation from working out, so would it be best to workout before bed or at night to aid in sleep? 3.what are your thoughts on nicotine? when I take a nicotine hit from an e-cigarette I get a nice buzz and I get alert and the mood gets better. do you think it is wise to use it daily or once a while?
what devices did you use for lllt for brain and what are your thoughts on veilight x-plus for brain inflam and tbi.
joe what would you recommend for me I am recovering from severe TBI with LAD I have brought brain inflam down quite a bit, also taking anti-inflammatories. but I have some sort of low-level chronic inflam there and have problems with brain fog/ mood/ energy. what are your recommendation for me to get healthy or normal? i am frustrated I'm doing everything right still have problems. please help I can be an experiment for you if you want to consult me. what are your thoughts on the hyperbaric chamber for me?
hey joe, I just did my self decode reports and want to start introducing the supplements, how would you suggest to see if a supplement is working for you? and for example, if i take htp and then want to take alpha gpc, would I stop htp and take alpha gpc alone or just take it on top of htp. also i have a chronic condition so if that changes things.

PAST WEBINARS

 VIP #40                                                         MAY 21, 2020

Question
Final note to my big questions below: I think it was vitamin K (K1, MK4, MK7) causing my BP issues!? I'm starting to take 10k D without any K. PS: What's the Group Consult for?
I have tried several times to unsubscribe from VIP service but you keep charging me. I have evidence from many emails and only one response. I really enjoyed for several years your service but this is unprofessional. I know you are probably not even aware of this and that this is not the place for this, but you should have venues to solve problems like this.
Do you know any particular hack/solution to overcome waking up at night at about 1-3 am? Most of the time I fall asleep very quickly, then I wake up after the first or second sleep cycle. Usually, I don't feel tired after and it is really hard to fall back to sleep. It takes much time for me to feel tired again and fall back to sleep again, but even when I can I have a lighter sleep. According to your sleep report, I have lower-than-average risk for insomnia-like symptoms.
A few other observations on top of my first message, My Oura is tracking a -5-8 dip in BPM at the moments I wake up (~2am, ~3:30, sometimes midnight). When I had a Fitbit it tracked a -7-10% dip in oxygen (Pulse Ox) around those same times (before megadosing D). With the D+licorice interaction I had super high and sensitive BPM during the day, so that still points me to aldosterone/etc imbalance. But are these ox/BPM dips related? Are they just sleep apnea? But if so, why at very specific times? I've been looking into trying nitric oxide supplementation but am not sure if it fits this picture?
I've gotten myself into an odd situation with Vitamin D so bear with me please. I've been chronically deficient (VDR SNPs confirmed, maybe absorption issues too?) so I feel I need to supplement for life, but I'd been neglecting it for years because no doctor prioritized it. So last October - November I megadosed 25k-70k daily for a few weeks to force my levels into optimal range (D3 + 3 Ks was most effective) , mainly because I was in pursuit of resolving a severe, chronic cluster of health issues: 1-3-day-long, post-meal "hangovers" involving lethargy, cognitive impairment, eye pain / uveitis, loss of appetite, and mood issues (which I'd asked you about a couple months ago too). I got a blood test and overshot it of course (196 ng/mL of 25OH with calcitriol at 80pg), yet had ZERO negative side effects. This megadosing experiment DID IMPROVE those symptoms which had not responded to anything else for three years, and then completely disappeared like a miracle with slippery elm! (So clearly there was a gut-immune connection; I found your Tregs article which seems relevant). HOWEVER, to try supporting my continuing adrenal/HPA fatigue. I experimented with about 3 days of licorice root/tea at the end of my megadosing phase and my blood pressure skyrocketed to scary levels. I took myself to MedExpress, before connecting the dots: stopping D immediately lowered the high daytime BP. But I was left in a pattern of 3am awakenings for months, finally resolved a few weeks ago with 3000mg (3x) Seriphos and eating glucose Extend bars before bed. (My hunger/metabolism is through the roof, along with shaky body temp / temp sensitivity) Then recently, some of those "hangover" symptoms popped back up. I connected the dots to being 4 months off D, so I took 45k again across two days. Maybe it was too much? Because my sleep has been disturbed with 2am AND 3-4am high BP awakenings, where I can't fall back to sleep after the second awakening. I finally realized this is more likely aldosterone than cortisol? This BP is very 'calm but heavy', whereas cortisol BP always had a clear physical-mental-emotional stress associated with it and responded to Seriphos. My 3x Seriphos before bed has lost its efficacy with this non-stress BP. Taking another 1x with the second awakening might be helping me get back to sleep 2-3 hours later, but also wipes out my morning cortisol/oomph. So. What body equilibrium/system involving D/aldosterone/cortisol/adrenals/electrolytes did licorice screw with, that taking D is producing aldosterone-based insomnia? What am I missing? Based on two blood tests 45 days apart, my 196 levels dropped to 78 at a rate of losing ~2.4ng / day, so I don't think I can go too long with out D. But it's like I traded severe gut-immune symptoms for crazy insomnia, and there's a balance in between that I'm missing and don't know how to get back to. I feel like if I'd never experimented with licorice (the one thing I didn't research enough in my whole life!!!), then the combo of D + slippery elm + glucose management + Seriphos would've supported all of my issues and left me in a good place. Eager for your insight. Thank you.
I was wondering if I could schedule an appointment with you. Brain fog has become a big part of my life, and it's really made working difficult. My forehead always feels tight and it has become very hard to concentrate. I've been trying to treat my brain fog but so far it has been to no avail. Any help would be immensely appreciated.
My DHEA is high, I don't take supplements. I can find lots of info about low DHEA but not high. What are the implications of having a high DHEA the blood test results came back saying 7.14 umol/L out of range
Any particular reason why NAC isn't in your regimen?
Do you have any advice on weaning off from Otrivine for someone who suffers allergic nasal congestion at night?
"HLA-DQ8 even without HLA-DQ2 still seems to confer a 5-10% risk of celiac disease. It seems that selfdecode does not report this risk as below ... ""rs7454108 tags the HLA-DQ8 haplotype"" https://www.snpedia.com/index.php/Celiac_disease ""DQ8-positive HLA-DQA1*03 and HLA-DQB1*0302 5%-10%"" https://www.ncbi.nlm.nih.gov/books/NBK1727/ ""rs7454108 is not linked to any genes. Your genotype is TT"" https://selfdecode.com/snp/rs7454108/ Am I missing something? Kind regards from New Zealand :)"
I just wrote in a question about RA/Carnivore. I meant to also write I am APOE 3/4 so how do I address the saturated fat issue? Thanks.
I am somewhere on the arthritis spectrum, possibly RA (it's painful and in all matching joints). Last summer I went carnivore which helped a ton, but a simultaneous large increase in a calcium supplement gave me C-Diff. My joint pain is unmanageable and I want to carefully return to as close to carnivore as possible. I think I need to keep some level of carb because I have Hashimotos and sleep/ feel better with it. Can you suggest how I would best do this? Soaked rice over vegetables? I've tried everything else- AIP, Keto, Paleo and the arthritis stays with me. Any other suggestions?

Ask Joe

Have a question that hasn’t been answered in this webinar? Ask Joe yourself and have it answered in an upcoming webinar

ASK JOE

Cancel Membership?

To cancel your membership, email us at [email protected]